Ventricular enlargement and mild cognitive impairment in early Parkinson's disease
نویسندگان
چکیده
منابع مشابه
Hippocampal and ventricular changes in Parkinson's disease mild cognitive impairment.
We analyzed T1-weighted brain magnetic resonance imaging data of 100 cognitively normal elderly controls (NC), 127 cognitively normal Parkinson's disease (PD; PDCN) and 31 PD-associated mild cognitive impairment (PDMCI) subjects from the Norwegian ParkWest study. Using automated segmentation methods, followed by the radial distance technique and multiple linear regression we studied the effect ...
متن کاملPredictors of Mild Cognitive Impairment in Early-Stage Parkinson's Disease
AIM The aim of this study was to identify mild cognitive deficits in Parkinson's disease (PD) prior to extensive neurodegeneration and to evaluate the extent to which dopamine depletion and other disease-related predictors can explain cognitive profiles. METHODS Neuropsychological performances of 40 nondemented early-stage PD patients and 42 healthy controls were compared across on or off dop...
متن کاملIdentification of mild cognitive impairment disease using brain functional connectivity and graph analysis in fMRI data
Background: Early diagnosis of patients in the early stages of Alzheimer's, known as mild cognitive impairment, is of great importance in the treatment of this disease. If a patient can be diagnosed at this stage, it is possible to treat or delay Alzheimer's disease. Resting-state functional magnetic resonance imaging (fMRI) is very common in the process of diagnosing Alzheimer's disease. In th...
متن کاملMild cognitive impairment represents early-stage Alzheimer disease.
BACKGROUND Mild cognitive impairment (MCI) is considered to be a transitional stage between aging and Alzheimer disease (AD). OBJECTIVE To determine whether MCI represents early-stage AD by examining its natural history and neuropathologic basis. DESIGN A prospective clinical and psychometric study of community-living elderly volunteers, both nondemented and minimally cognitively impaired, ...
متن کاملCharacterizing mild cognitive impairment in Parkinson's disease.
There is growing interest in identifying Parkinson's disease (PD) patients with mild cognitive impairment (PD-MCI), but widely disparate criteria have been used. We assessed 143 PD patients and 50 matched controls on 20 measures across 4 cognitive domains (executive function, attention and working memory, learning and memory, visuoperception). Twenty-four patients met criteria for dementia (PD-...
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ژورنال
عنوان ژورنال: Movement Disorders
سال: 2010
ISSN: 0885-3185
DOI: 10.1002/mds.23443